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Title
Estimating the resources needed and savings anticipated from roll-out of adult male circumcision in sub-Saharan Africa |
Full text
http://hdl.handle.net/1765/15219 |
Date
2008 |
Author(s)
Auvert, B.; Marseille, E.; Korenromp, E.L.; Lloyd-Smith, J.; Sitta, R.; Taljaard, D.; Pretorius, C.; Williams, B.; Kahn, J.G. |
Abstract
Background: Trials in Africa indicate that medical adult male circumcision (MAMC) reduces the risk of HIV by 60%. MAMC may avert 2 to 8 million HIV infections over 20 years in sub-Saharan Africa and cost less than treating those who would have been infected. This paper estimates the financial and human resources required to roll out MAMC and the net savings due to reduced infections. Methods: We developed a model which included costing, demography and HIV epidemiology. We used it to investigate 14 countries in sub-Saharan Africa where the prevalence of male circumcision was lower than 80% and HIV prevalence among adults was higher than 5%, in addition to Uganda and the Nyanza province in Kenya. We assumed that the roll-out would take 5 years and lead to an MC prevalence among adult males of 85%. We also assumed that surgery would be done as it was in the trials. We calculated public program cost, number of full-time circumcisers and net costs or savings when adjusting for averted HIV treatments. Costs were in USD, discounted to 2007. 95% percentile intervals (95% PI) were estimated by Monte Carlo simulations. Results: In the first 5 years the number of circumcisers needed was 2 282 (95% PI: 2 018 to 2 959), or 0.24 (95% PI: 0.21 to 0.31) per 10 000 adults. In years 6-10, the number of circumcisers needed fell to 513 (95% PI: 452 to 664). The estimated 5-year cost of rolling out MAMC in the public sector was $919 million (95% PI: 726 to 1 245).The cumulative net cost over the first 10 years was $672 million (95% PI: 437 to 1 021) and over 20 years there were net savings of $2.3 billion (95% PI: 1.4 to 3.4). Conclusion: A rapid roll-out of MAMC in sub-Saharan Africa requires substantial funding and a high number of circumcisers for the first five years. These investments are justified by MAMC's substantial health benefits and the savings accrued by averting future HIV infections. Lower ongoing costs and continued care savings suggest long-term sustainability. Copyright: © 2008 Auvert et al. |
Subject(s)
Africa; article; circumcision; cost control; cost effectiveness analysis; economic evaluation; health care cost; health care financing; health care need; health care planning; health program; human; Human immunodeficiency virus infection; Human immunodeficiency virus prevalence; male; public health; adult; Africa south of the Sahara; economics; middle aged; statistics; Adult; Africa South of the Sahara; Circumcision; Male; Health Resources; HIV Infections; Humans; male; Middle Aged |
Language
en |
Type of publication
Article |
Identifier
1932-6203; PLoS ONE, Volume 3, Issue 8, 6 August 2008, Article number e2679; 10.1371/journal.pone.0002679 |
Repository
Rotterdam - Erasmus University
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Added to C-A: 2009-06-22;10:20:08 |
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