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Title Biomarker testing to estimate under-reported heavy alcohol consumption by persons with HIV initiating ART in Uganda.
Full text https://escholarship.org/uc/item/3fc677tk
Date 2010
Author(s) Hahn, Judith A; Bwana, Mwebesa B; Javors, Martin A; Martin, Jeffrey N; Emenyonu, Nneka I; Bangsberg, David R
Abstract Alcohol affects the transmission and treatment of HIV, yet may be under-reported in resource-limited settings. We compared self-reported alcohol consumption with levels of plasma carbohydrate-deficient transferrin (%CDT), a biomarker of heavy alcohol consumption, in persons initiating antiretroviral therapy in Uganda. Almost seven percent (6.7%) of persons reporting abstaining and 10% reporting consuming 1-40 drinks in the prior month tested positive for %CDT, and actual under-report may be higher due to low sensitivity of %CDT. These results suggest likely under-report in those reporting abstaining and current drinking. Improved identification of heavy alcohol consumption is needed for research and clinical purposes.
Subject(s) Humans; HIV Infections; Alcoholism; gamma-Glutamyltransferase; Transferrin; Antiretroviral Therapy; Highly Active; Cohort Studies; Alcohol Drinking; Adult; Aged; Middle Aged; Uganda; Female; Male; Young Adult; Self Report; Biomarkers; Carbohydrate-deficient transferrin; Biological markers; Alcohol drinking; HIV; Antiretroviral therapy; Clinical Research; Behavioral and Social Science; HIV/AIDS; Substance Abuse; Alcoholism; Alcohol Use and Health; Stroke; Cancer; Public Health; Public Health and Health Services; Social Work
Coverage 1265 - 1268
Publisher eScholarship, University of California
Type of publication article
Format application/pdf
Source AIDS and behavior, vol 14, iss 6
Rights public
Identifier qt3fc677tk
Repository Berkeley - University of California
Added to C-A: 2022-06-09;08:31:57