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Title
Maternal PrEP Use in HIV-Uninfected Pregnant Women in South Africa: Role of Stigma in PrEP Initiation, Retention and Adherence. |
Full text
https://escholarship.org/uc/item/6416n8x1 |
Date
2022 |
Author(s)
Moran, Alexander; Mashele, Nyiko; Mvududu, Rufaro; Gorbach, Pamina; Bekker, Linda-Gail; Coates, Thomas J; Myer, Landon; Joseph Davey, Dvora |
Abstract
Pregnant women in sub-Saharan Africa are at high risk of HIV acquisition and require effective methods to prevent HIV. In a cohort of pregnant women offered Pre-exposure prophylaxis (PrEP), we evaluate the relationship between internalized and anticipated stigma and PrEP initiation at first antenatal visit, 3-month continuation and adherence using multivariable logistic regression. High internalized and anticipated PrEP stigma are associated with lower PrEP care initiation at first antenatal visit (aOR internalized stigma = 0.06; 95% CI = 0.03-0.11 and aOR anticipated stigma = 0.55; 95% CI = 0.31-1.00) compared to women with low reported stigma, after controlling for covariates. Women whose partners have not been tested for HIV or whose serostatus remains unknown have 1.6-times odds of PrEP retention at 3-months compared to women whose partners have been tested (aOR = 1.60; 95% CI = 1.02-2.52) after adjusting for covariates. PrEP counseling and maternal PrEP interventions must consider individual- and relational-level interventions to overcome anticipated PrEP stigma and other barriers to PrEP initiation and adherence. |
Subject(s)
Humans; HIV Infections; Anti-HIV Agents; Pregnancy; Pregnant Women; South Africa; Female; Pre-Exposure Prophylaxis; HIV prophylaxis; PrEP; Stigma; Pediatric; Mental Health; Behavioral and Social Science; Pediatric AIDS; Clinical Research; Prevention; HIV/AIDS; Reproductive health and childbirth; Infection; Public Health and Health Services; Social Work; Public Health |
Coverage
205 - 217 |
Publisher
eScholarship, University of California |
Type of publication
article |
Format
application/pdf |
Source
AIDS and behavior, vol 26, iss 1 |
Rights
public |
Identifier
qt6416n8x1 |
Repository
Berkeley - University of California
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Added to C-A: 2022-10-10;08:53:35 |
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